cascade.graph.annotate_explanation

cascade.graph.annotate_explanation(digraph, ctfact, causal_map, cutoff=0.1)

Annotate counterfactual explanation to the causal graph

Parameters:

• digraph (DiGraph) – Causal graph (from export_causal_graph())

• ctfact (AnnData) – Dataset with counterfactual explanation (from explain())

• causal_map (DataFrame) – Causal map (from export_causal_map())

• cutoff (float) – Minimal cutoff of absolute total change for a gene to be annotated with contributions (small changes cannot be reliably annotated)

Return type:

DiGraph

Returns:

Annotated causal graph

Tip

It is strongly recommended to limit cells to a single perturbation for use as ctfact.